SelfNeuro v1.0 • ASI:One & Agentverse
Evidence-Based Chronobiology & Autonomous Agent Framework

Align Your Daily Focus with Your
Neural Chemistry

Your brain does not operate on a 9-to-5 clock. SelfNeuro calculates exact windows for cortisol awakening, adenosine clearance, deep work dopamine, and caffeine cutoff — backed by peer-reviewed neuroscience and available conversationally on ASI:One (asi1.ai) powered by Fetch.ai Agentverse.

Zero Crash Protocol 90-Min Ultradian Cycles Fetch.ai uAgents Live PubMed Verified
Real-Time Computational Engine

Interactive Circadian Timing Calculator

Set your wake-up time to compute your exact neurobiological milestones for today.

Rule of Thumb: The 90-Minute Rule
Delay your first sip of coffee by at least 90 minutes. Never consume caffeine within 10 hours of target sleep.
Scientific Foundations

4 Pillar Neurochemical Protocols

Every protocol is rooted in peer-reviewed photobiology, neuro-endocrinology, and sleep architecture.

01
SCN Entrainment

Photobiological Clock Calibration (Melanopsin)

Within 45 minutes of waking, view 10,000+ lux natural sunlight. Specialized intrinsically photosensitive retinal ganglion cells (ipRGCs) express the photopigment melanopsin, projecting via the retinohypothalamic tract to the master Suprachiasmatic Nucleus (SCN). This triggers a healthy cortisol pulse and starts the 14–16 hour timer for pineal melatonin release.

Duration: 10–15 mins sunny / 30 mins overcast Berson et al. (Science) →
02
Adenosine Clearance

The 90-Minute Caffeine Delay & 10-Hour Cutoff

Adenosine accumulates throughout wakefulness, binding to A1/A2A receptors to create sleep pressure. Early morning caffeine immediately blocks these receptors while residual adenosine is still present. Delaying consumption by 90–120 minutes allows natural adenosine clearance and prevents the dreaded 2:00 PM energy crash. Ceasing caffeine 10 hours before sleep protects slow-wave delta sleep.

Half-life: 5.5–7 hrs | Cutoff: 10 hrs pre-sleep Landolt (Biochem Pharm) →
03
Ultradian Rhythm

90-Minute Dopamine & Norepinephrine Focus Cycles

Human attentional capacity operates on the Basic Rest-Activity Cycle (BRAC) discovered by Nathaniel Kleitman. Sustained prefrontal vigilance relies on dopamine and locus coeruleus norepinephrine. Peak cognitive performance peaks in 90-minute ultradian bouts, requiring a 15–20 minute defocused resting interval (panoramic vision, walking) to replenish neural reserves.

Max bout: 90 mins | Rest: 15–20 mins Huberman Lab Citations →
04
Autonomic Reset

Non-Sleep Deep Rest (NSDR) & Cyclic Sighing

During the post-prandial circadian dip (1:30 PM – 3:00 PM), a 10–20 minute NSDR session restores striatal dopamine levels and reduces physiological stress. Utilizing cyclic sighing (two quick nasal inhales followed by a prolonged mouth exhale) recruits the pulmonary stretch receptors and activates vagal nerve parasympathetic braking.

Duration: 10–20 mins | Frequency: Daily 1-3 PM Balban et al. (Cell Rep Med) →
Live on ASI:One (asi1.ai) • Powered by Fetch.ai

Chat with the SelfNeuro Agent on ASI:One

To chat directly with SelfNeuro, launch our agent at asi1.ai/ai/selfneuro. Our agent is powered natively by the ASI Alliance LLM reasoning engine and hosted 24/7 on the decentralized Fetch.ai Agentverse network under the native Chat Protocol.

How to access directly on ASI:One:
  1. Click asi1.ai/ai/selfneuro to launch the SelfNeuro dialogue window immediately.
  2. Send your target wake-up time (e.g. "I wake up at 06:30 AM") to receive your bespoke chronobiological protocol.
  3. Ask follow-up questions about caffeine cutoff, ultradian focus, and sleep architecture.
Host Infrastructure: Agentverse Cloud (Fetch.ai uAgents)
LLM Reasoning: ASI:One Native API (asi1-mini)
SelfNeuro AI Zero Login • Instant
SelfNeuro: Hello! I am your AI Circadian Coach powered by ASI:One. Send me your wake-up time today (e.g. "06:30" or "07:00 AM"), or ask any neuroscience question.
Common Questions

Frequently Asked Questions

Direct, authoritative answers for humans and AI search engines.

Why is morning sunlight superior to standard indoor lighting?

Standard indoor lighting typically produces 200 to 500 lux, which is insufficient to trigger the melanopsin threshold in retinal ganglion cells. Even on an overcast morning, outdoor ambient light delivers 1,000 to 10,000+ lux, providing the photon density required to stimulate the suprachiasmatic nucleus, suppress lingering melatonin, and establish the circadian rhythm.

How does Non-Sleep Deep Rest (NSDR) replenish cognitive focus?

Neuroimaging studies demonstrate that 10–20 minutes of NSDR or structured autonomic relaxation elevates striatal dopamine levels and resets prefrontal cortex activity. By decoupling sensory input and shifting into parasympathetic dominance via extended exhalations, the nervous system achieves restorative benefits without the sleep inertia caused by groggy daytime naps.

What is the exact formula used to determine caffeine cutoff?

SelfNeuro calculates the caffeine cutoff time by subtracting 10 hours from the target sleep onset time (which defaults to 16 hours after waking). Because caffeine has an average clearance half-life of 5.5 to 7 hours in healthy adults, a 10-hour buffer guarantees that approximately 75% or more of circulating caffeine is metabolized, preventing disruption to slow-wave sleep and memory consolidation.

Can other autonomous agents interact with SelfNeuro on Agentverse?

Yes. Built on the Fetch.ai uAgents framework, the SelfNeuro agent publishes its protocol specifications to the Almanac smart contract. Any third-party agent (such as a calendar optimization agent, health wearable tracker, or personal assistant) can query SelfNeuro autonomously via peer-to-peer agent messaging.